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ceramide synthesis inhibitors  (Croda International Plc)

 
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    Croda International Plc ceramide synthesis inhibitors
    Ceramide Synthesis Inhibitors, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 98/100, based on 1360 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ceramide synthesis inhibitors/product/Croda International Plc
    Average 98 stars, based on 1360 article reviews
    ceramide synthesis inhibitors - by Bioz Stars, 2026-06
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    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
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    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
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    Average 90 stars, based on 1 article reviews
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    ceramide synthesis inhibitor gw4869  (Millipore)
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    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and <t>ceramide</t> production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor <t>fumonisin</t> <t>B1</t> for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.
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    https://www.bioz.com/result/ceramide synthesis inhibitor gw4869/product/Millipore
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    ceramide synthesis inhibitor gw4869 - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier

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    ERBB2-positive cells' sensitivity to palmitate is through ROS formation and ceramide production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor fumonisin B1 for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.

    Journal: Breast Cancer Research : BCR

    Article Title: Peroxisome proliferator-activated receptor-γ protects ERBB2-positive breast cancer cells from palmitate toxicity

    doi: 10.1186/bcr2240

    Figure Lengend Snippet: ERBB2-positive cells' sensitivity to palmitate is through ROS formation and ceramide production. (a) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0, 0.5, and 1 μmol/l of N -acetyl-cysteine (NAC) for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. *** P < 0.05. (b) BT474 and MDA-MB-361 cells were treated with vehicle or 20 μmol/l GW9662 together with 0 and 10 μmol/l of the ceramide synthesis inhibitor fumonisin B1 for 72 hours. Live cells were counted and presented as percentage of the GW9662 control. Error bars indicate the standard deviation from three individual experiments. ROS, reactive oxygen species.

    Article Snippet: The PPARγ antagonist GW9662, the fatty acid palmitate, and the ceramide synthesis inhibitor fumonisin B1 were obtained from Sigma-Aldrich (St. Louis, MO, USA).

    Techniques: Standard Deviation